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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFATC3 All Species: 18.18
Human Site: S180 Identified Species: 44.44
UniProt: Q12968 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12968 NP_004546.1 1075 115594 S180 R S W F S D A S S C E S L S H
Chimpanzee Pan troglodytes XP_001167633 1075 115585 S180 R S W F S D A S S C E S L S H
Rhesus Macaque Macaca mulatta XP_001088166 812 87865
Dog Lupus familis XP_536809 1075 115741 S180 R S W F S D A S S C E S L S H
Cat Felis silvestris
Mouse Mus musculus P97305 1075 115432 S180 R S W F S D A S S C E S L S H
Rat Rattus norvegicus NP_001101917 1068 115235 S181 R S W F S D A S S C E S L S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505280 629 67466
Chicken Gallus gallus XP_414078 1211 130585 A302 S R S W F S D A S S C E S I S
Frog Xenopus laevis NP_001082217 884 97675 E23 I F G E E S L E N H D S A D I
Zebra Danio Brachydanio rerio XP_690273 1074 115220 D198 S H V Y D D V D S E L N E A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 37.2 93.4 N.A. 90.4 87 N.A. 42.7 66.6 52.5 60.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 47.9 96.1 N.A. 93.2 90.8 N.A. 46.7 74.9 64.3 70.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 0 6.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 0 20 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 50 10 0 0 0 0 10 10 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 50 10 0 0 0 0 % C
% Asp: 0 0 0 0 10 60 10 10 0 0 10 0 0 10 0 % D
% Glu: 0 0 0 10 10 0 0 10 0 10 50 10 10 0 0 % E
% Phe: 0 10 0 50 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 50 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 10 0 50 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 50 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 50 10 0 50 20 0 50 70 10 0 60 10 50 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 50 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _